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TargetHematopoietic protein-tyrosine phosphatase (HEPTP)
LigandBDBM76336
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of compounds that inhibit HePTP
IC50 1520±n/a nM
Citation PubChem, PC Dose Response confirmation of compounds that inhibit HePTP PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Hematopoietic protein-tyrosine phosphatase (HEPTP)
Name:Hematopoietic protein-tyrosine phosphatase (HEPTP)
Synonyms:He-PTP | Hematopoietic protein-tyrosine phosphatase | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:Protein
Mol. Mass.:40530.79
Organism:Homo sapiens (Human)
Description:P35236
Residue:360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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  Blast E-value cutoff:
BDBM76336
NameBDBM76336
Synonyms:6-bromanyl-2-pyridin-2-yl-N-pyridin-4-yl-quinoline-4-carboxamide | 6-bromo-2-(2-pyridinyl)-N-4-pyridinyl-4-quinolinecarboxamide | 6-bromo-2-(2-pyridinyl)-N-pyridin-4-yl-4-quinolinecarboxamide | 6-bromo-2-(2-pyridyl)-N-(4-pyridyl)cinchoninamide | 6-bromo-2-pyridin-2-yl-N-pyridin-4-ylquinoline-4-carboxamide | MLS000672592 | SMR000295450 | cid_1261644
TypeSmall organic molecule
Emp. Form.C20H13BrN4O
Mol. Mass.405.247
SMILESBrc1ccc2nc(cc(C(=O)Nc3ccncc3)c2c1)-c1ccccn1
Structure
n/a