Reaction Details Report a problem with these data
Target
Protein RecA
Ligand
BDBM42255
Substrate
n/a
Meas. Tech.
Intein inhibitors as potential Tuberculosis drugs
IC50
88640±n/a nM
Citation
 PubChem, PC Intein inhibitors as potential Tuberculosis drugs PubChem Bioassay (2010)[AID] 
Target
Name:
Protein RecA
Synonyms:
DNA recombination protein RecA | RECA_MYCTU | recA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
85386.52
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15609874
Residue:
790
Sequence:
MTQTPDREKALELAVAQIEKSYGKGSVMRLGDEARQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQAAGGVAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLMSQALRKMTGALNNSGTTAIFINQLRDKIGVMFGSPETTTGGKALKFYASVRMDVRRVETLKDGTNAVGNRTRVKVVKNKCLAEGTRIFDPVTGTTHRIEDVVDGRKPIHVVAAAKDGTLHARPVVSWFDQGTRDVIGLRIAGGAIVWATPDHKVLTEYGWRAAGELRKGDRVAQPRRFDGFGDSAPIPADHARLLGYLIGDGRDGWVGGKTPINFINVQRALIDDVTRIAATLGCAAHPQGRISLAIAHRPGERNGVADLCQQAGIYGKLAWEKTIPNWFFEPDIAADIVGNLLFGLFESDGWVSREQTGALRVGYTTTSEQLAHQIHWLLLRFGVGSTVRDYDPTQKRPSIVNGRRIQSKRQVFEVRISGMDNVTAFAESVPMWGPRGAALIQAIPEATQGRRRGSQATYLAAEMTDAVLNYLDERGVTAQEAAAMIGVASGDPRGGMKQVLGASRLRRDRVQALADALDDKFLHDMLAEELRYSVIREVLPTRRARTFDLEVEELHTLVAEGVVVHNCSPPFKQAEFDILYGKGISREGSLIDMGVDQGLIRKSGAWFTYEGEQLGQGKENARNFLVENADVADEIEKKIKEKLGIGAVVTDDPSNDGVLPAPVDF
  
Inhibitor
Name:
BDBM42255
Synonyms:
MLS000391861 | N-[3-[(1,1-diketothiolan-3-yl)-methyl-amino]-1,4-diketo-2-naphthyl]benzamide | N-[3-[(1,1-dioxo-3-thiolanyl)-methylamino]-1,4-dioxo-2-naphthalenyl]benzamide | N-[3-[(1,1-dioxothiolan-3-yl)-methylamino]-1,4-dioxonaphthalen-2-yl]benzamide | N-[3-[[1,1-bis(oxidanylidene)thiolan-3-yl]-methyl-amino]-1,4-bis(oxidanylidene)naphthalen-2-yl]benzamide | SMR000260894 | cid_3342467
Type:
Small organic molecule
Emp. Form.:
C22H20N2O5S
Mol. Mass.:
424.47
SMILES:
CN(C1CCS(=O)(=O)C1)C1=C(NC(=O)c2ccccc2)C(=O)c2ccccc2C1=O |c:10|
Structure:
Search PDB for entries with ligand similarity: