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Target
Protein RecA
Ligand
BDBM70869
Substrate
n/a
Meas. Tech.
Intein inhibitors as potential Tuberculosis drugs
IC50
52060±n/a nM
Citation
 PubChem, PC Intein inhibitors as potential Tuberculosis drugs PubChem Bioassay (2010)[AID] 
Target
Name:
Protein RecA
Synonyms:
DNA recombination protein RecA | RECA_MYCTU | recA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
85386.52
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15609874
Residue:
790
Sequence:
MTQTPDREKALELAVAQIEKSYGKGSVMRLGDEARQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQAAGGVAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLMSQALRKMTGALNNSGTTAIFINQLRDKIGVMFGSPETTTGGKALKFYASVRMDVRRVETLKDGTNAVGNRTRVKVVKNKCLAEGTRIFDPVTGTTHRIEDVVDGRKPIHVVAAAKDGTLHARPVVSWFDQGTRDVIGLRIAGGAIVWATPDHKVLTEYGWRAAGELRKGDRVAQPRRFDGFGDSAPIPADHARLLGYLIGDGRDGWVGGKTPINFINVQRALIDDVTRIAATLGCAAHPQGRISLAIAHRPGERNGVADLCQQAGIYGKLAWEKTIPNWFFEPDIAADIVGNLLFGLFESDGWVSREQTGALRVGYTTTSEQLAHQIHWLLLRFGVGSTVRDYDPTQKRPSIVNGRRIQSKRQVFEVRISGMDNVTAFAESVPMWGPRGAALIQAIPEATQGRRRGSQATYLAAEMTDAVLNYLDERGVTAQEAAAMIGVASGDPRGGMKQVLGASRLRRDRVQALADALDDKFLHDMLAEELRYSVIREVLPTRRARTFDLEVEELHTLVAEGVVVHNCSPPFKQAEFDILYGKGISREGSLIDMGVDQGLIRKSGAWFTYEGEQLGQGKENARNFLVENADVADEIEKKIKEKLGIGAVVTDDPSNDGVLPAPVDF
  
Inhibitor
Name:
BDBM70869
Synonyms:
5-[(4-chloro-3-nitro-phenyl)sulfonylamino]-2-hydroxy-benzoic acid [2-keto-2-[1-(2-norbornyl)ethylamino]ethyl] ester | 5-[(4-chloro-3-nitrophenyl)sulfonylamino]-2-hydroxybenzoic acid [2-[1-(3-bicyclo[2.2.1]heptanyl)ethylamino]-2-oxoethyl] ester | MLS000418671 | SMR000247531 | [2-[1-(3-bicyclo[2.2.1]heptanyl)ethylamino]-2-oxidanylidene-ethyl] 5-[(4-chloranyl-3-nitro-phenyl)sulfonylamino]-2-oxidanyl-benzoate | [2-[1-(3-bicyclo[2.2.1]heptanyl)ethylamino]-2-oxoethyl] 5-[(4-chloro-3-nitrophenyl)sulfonylamino]-2-hydroxybenzoate | cid_3947477
Type:
Small organic molecule
Emp. Form.:
C24H26ClN3O8S
Mol. Mass.:
551.997
SMILES:
[H]C12CCC([H])(C1)C(C2)C(C)NC(=O)COC(=O)c1cc(NS(=O)(=O)c2ccc(Cl)c(c2)[N+]([O-])=O)ccc1O |TLB:9:7:6:3.2|
Structure:
Search PDB for entries with ligand similarity: