Reaction Details Report a problem with these data
Target
Caspase-7
Ligand
BDBM77497
Substrate
n/a
Meas. Tech.
Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7
EC50
>85222±n/a nM
Citation
 PubChem, PC Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 PubChem Bioassay (2010)[AID] 
Target
Name:
Caspase-7
Synonyms:
Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase
Type:
Enzyme
Mol. Mass.:
34273.91
Organism:
Homo sapiens (Human)
Description:
P55210
Residue:
303
Sequence:
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
  
Inhibitor
Name:
BDBM77497
Synonyms:
MLS000522781 | N-[2-[1-(4-methylbenzyl)benzimidazol-2-yl]ethyl]acetamide | N-[2-[1-[(4-methylphenyl)methyl]-2-benzimidazolyl]ethyl]acetamide | N-[2-[1-[(4-methylphenyl)methyl]benzimidazol-2-yl]ethyl]acetamide | N-[2-[1-[(4-methylphenyl)methyl]benzimidazol-2-yl]ethyl]ethanamide | SMR000128047 | cid_3160764
Type:
Small organic molecule
Emp. Form.:
C19H21N3O
Mol. Mass.:
307.3895
SMILES:
CC(=O)NCCc1nc2ccccc2n1Cc1ccc(C)cc1
Structure:
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