Reaction Details Report a problem with these data
Target
Caspase-7
Ligand
BDBM77505
Substrate
n/a
Meas. Tech.
Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7
EC50
>85267±n/a nM
Citation
 PubChem, PC Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 PubChem Bioassay (2010)[AID] 
Target
Name:
Caspase-7
Synonyms:
Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase
Type:
Enzyme
Mol. Mass.:
34273.91
Organism:
Homo sapiens (Human)
Description:
P55210
Residue:
303
Sequence:
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
  
Inhibitor
Name:
BDBM77505
Synonyms:
1-[[4-(diethylamino)benzylidene]amino]-3-(2-furfuryl)thiourea | 1-[[4-(diethylamino)phenyl]methylideneamino]-3-(2-furanylmethyl)thiourea | 1-[[4-(diethylamino)phenyl]methylideneamino]-3-(furan-2-ylmethyl)thiourea | 4-(diethylamino)benzaldehyde N-(2-furylmethyl)thiosemicarbazone | MLS000701374 | SMR000225232 | cid_1226537
Type:
Small organic molecule
Emp. Form.:
C17H22N4OS
Mol. Mass.:
330.448
SMILES:
CCN(CC)c1ccc(C=NNC(=S)NCc2ccco2)cc1 |w:10.10|
Structure:
Search PDB for entries with ligand similarity: