Reaction Details Report a problem with these data
Target
RecBCD enzyme subunit RecD
Ligand
BDBM73790
Substrate
n/a
Meas. Tech.
Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD
IC50
>118481±n/a nM
Citation
 PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay (2010)[AID] 
Target
Name:
RecBCD enzyme subunit RecD
Synonyms:
RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
66906.68
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130723
Residue:
608
Sequence:
MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE
  
Inhibitor
Name:
BDBM73790
Synonyms:
(4-Oxo-2-{[1-pyridin-2-yl-meth-(E)-ylidene]-hydrazono}-thiazolidin-5-yl)-acetic acid | 2-[4-keto-2-[N'-(2-pyridylmethylene)hydrazino]-2-thiazolin-5-yl]acetic acid | 2-[4-oxidanylidene-2-[2-(pyridin-2-ylmethylidene)hydrazinyl]-1,3-thiazol-5-yl]ethanoic acid | 2-[4-oxo-2-[2-(2-pyridinylmethylidene)hydrazinyl]-5-thiazolyl]acetic acid | 2-[4-oxo-2-[2-(pyridin-2-ylmethylidene)hydrazinyl]-1,3-thiazol-5-yl]acetic acid | MLS001044506 | SMR000415001 | cid_3832830
Type:
Small organic molecule
Emp. Form.:
C11H10N4O3S
Mol. Mass.:
278.287
SMILES:
OC(=O)Cc1sc(N=NCc2ccccn2)nc1O |w:7.6|
Structure:
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