Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM76315
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay
IC50
5670±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM76315
Synonyms:
(E)-N'-(2-propoxyphenyl)-2-butenediamide | (E)-N'-(2-propoxyphenyl)but-2-enediamide | MLS000531941 | N-(2-propoxyphenyl)-2-butenediamide | SMR000136884 | cid_1556906
Type:
Small organic molecule
Emp. Form.:
C13H16N2O3
Mol. Mass.:
248.2777
SMILES:
CCCOc1ccccc1NC(=O)\C=C\C(N)=O
Structure:
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