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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78808
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
IC50
1022±24 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78808
Synonyms:
2-[4-[2-(4-fluorophenyl)sulfanylethyl]pyridin-1-ium-1-yl]-1-phenyl-ethanone;bromide | 2-[4-[2-(4-fluorophenyl)sulfanylethyl]pyridin-1-ium-1-yl]-1-phenylethanone;bromide | 2-[4-[2-[(4-fluorophenyl)thio]ethyl]-1-pyridin-1-iumyl]-1-phenylethanone;bromide | 2-[4-[2-[(4-fluorophenyl)thio]ethyl]pyridin-1-ium-1-yl]-1-phenyl-ethanone;bromide | 4-{2-[(4-fluorophenyl)thio]ethyl}-1-(2-oxo-2-phenylethyl)pyridinium | MLS000722811 | SMR000304807 | cid_2827177
Type:
Small organic molecule
Emp. Form.:
C21H19FNOS
Mol. Mass.:
352.445
SMILES:
Fc1ccc(SCCc2cc[n+](CC(=O)c3ccccc3)cc2)cc1
Structure:
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