Reaction Details Report a problem with these data
Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM43864
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
IC50
1700±28 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM43864
Synonyms:
2-chloranyl-N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]benzene-1,4-dicarboxamide | 2-chloro-1-N,4-N-bis[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]benzene-1,4-dicarboxamide | 2-chloro-N,N''''-bis[4-(2-imidazolin-2-yl)phenyl]terephthalamide | 2-chloro-N,N''-bis[4-(2-imidazolin-2-yl)phenyl]terephthalamide | 2-chloro-N,N'-bis[4-(2-imidazolin-2-yl)phenyl]terephthalamide | 2-chloro-N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]benzene-1,4-dicarboxamide | Glycopeptide, 3b | HR 2198 | MLS000737368 | SMR000528281 | cid_65558
Type:
Peptide
Emp. Form.:
C26H23ClN6O2
Mol. Mass.:
486.953
SMILES:
Clc1cc(ccc1C(=O)Nc1ccc(cc1)C1=NCCN1)C(=O)Nc1ccc(cc1)C1=NCCN1 |t:18,34|
Structure:
Search PDB for entries with ligand similarity: