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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM64766
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
IC50
1585±46 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM64766
Synonyms:
MLS001239923 | N-({2-[(2,4-dimethylphenoxy)acetyl]hydrazino}carbothioyl)cyclopropanecarboxamide | N-[[2-(2,4-dimethylphenoxy)ethanoylamino]carbamothioyl]cyclopropanecarboxamide | N-[[[2-(2,4-dimethylphenoxy)-1-oxoethyl]hydrazo]-sulfanylidenemethyl]cyclopropanecarboxamide | N-[[[2-(2,4-dimethylphenoxy)acetyl]amino]carbamothioyl]cyclopropanecarboxamide | N-[[[2-(2,4-dimethylphenoxy)acetyl]amino]thiocarbamoyl]cyclopropanecarboxamide | SMR000673399 | cid_1791313
Type:
Small organic molecule
Emp. Form.:
C15H19N3O3S
Mol. Mass.:
321.395
SMILES:
Cc1ccc(OCC(=O)NNC(=S)NC(=O)C2CC2)c(C)c1
Structure:
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