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Target
X-box-binding protein 1
Ligand
BDBM52441
Substrate
n/a
Meas. Tech.
XBP1 DR counterscreen for CHOP
IC50
160±n/a nM
Citation
 PubChem, PC XBP1 DR counterscreen for CHOP PubChem Bioassay (2011)[AID] 
Target
Name:
X-box-binding protein 1
Synonyms:
TREB5 | XBP1 | XBP1_HUMAN | XBP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28704.14
Organism:
Homo sapiens (Human)
Description:
gi_47678753
Residue:
261
Sequence:
MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQLSPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVPYQPPFLCQWGRHQPSWKPLMN
  
Inhibitor
Name:
BDBM52441
Synonyms:
2-[(2,4,6-Trioxo-1-m-tolyl-tetrahydro-pyrimidin-5-ylidenemethyl)-amino]-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid ethyl ester | 2-[[(Z)-[1-(3-methylphenyl)-2,4,6-trioxo-1,3-diazinan-5-ylidene]methyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl ester | 2-[[(Z)-[2,4,6-triketo-1-(m-tolyl)hexahydropyrimidin-5-ylidene]methyl]amino]-4,5,6,7-tetrahydrobenzothiophene-3-carboxylic acid ethyl ester | MLS000564600 | SMR000175631 | cid_5758715 | ethyl 2-[[(Z)-[1-(3-methylphenyl)-2,4,6-trioxo-1,3-diazinan-5-ylidene]methyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate | ethyl 2-[[(Z)-[1-(3-methylphenyl)-2,4,6-tris(oxidanylidene)-1,3-diazinan-5-ylidene]methyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C23H23N3O5S
Mol. Mass.:
453.511
SMILES:
CCOC(=O)c1c2CCCCc2sc1N=Cc1c(O)n(-c2cccc(C)c2)c(=O)[nH]c1=O |w:14.15|
Structure:
Search PDB for entries with ligand similarity: