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Target
Perilipin-1
Ligand
BDBM48544
Substrate
n/a
Meas. Tech.
Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain
IC50
20829±n/a nM
Citation
 PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1 (PLIN1) (2K validation set) PubChem Bioassay (2011)[AID] 
Target
Name:
Perilipin-1
Synonyms:
PERI | PLIN | PLIN1 | PLIN1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55988.69
Organism:
Homo sapiens (Human)
Description:
gi_223718203
Residue:
522
Sequence:
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTDTEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS
  
Inhibitor
Name:
BDBM48544
Synonyms:
3a-[(E)-2-(2-furanyl)ethenyl]-4,4-dimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one | 3a-[(E)-2-(2-furyl)vinyl]-4,4-dimethyl-1,3-dihydroimidaz[1,2-a]indol-2-one | 3a-[(E)-2-(furan-2-yl)ethenyl]-4,4-dimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one | MLS000082334 | SMR000045828 | cid_5389882
Type:
Small organic molecule
Emp. Form.:
C18H18N2O2
Mol. Mass.:
294.3477
SMILES:
CC1(C)c2ccccc2N2CC(=O)NC12\C=C\c1ccco1
Structure:
Search PDB for entries with ligand similarity: