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Target
Perilipin-5
Ligand
BDBM79411
Substrate
n/a
Meas. Tech.
Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain
IC50
4850±n/a nM
Citation
 PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) (2K validation set) PubChem Bioassay (2011)[AID] 
Target
Name:
Perilipin-5
Synonyms:
LSDP5 | OXPAT | PAT-1 | PLIN5 | PLIN5_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50774.20
Organism:
Homo sapiens (Human)
Description:
gi_116292172
Residue:
463
Sequence:
MSEEEAAQIPRSSVWEQDQQNVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSACRLAENCVCGLTTRALDHAQPLLEHLQPQLATMNSLACRGLDKLEEKLPFLQQPSETVVTSAKDVVASSVTGVVDLARRGRRWSVELKRSVSHAVDVVLEKSEELVDHFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLGSLSARIRHLAYEHSVGKLRQSKHRAQDTLAQLQETLELIDHMQCGVTPTAPACPGKVHELWGEWGQRPPESRRRSQAELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVAEVRRSVDALQTAFADARCFRDVPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGPFAPILVERPEPLPDLADLVDEVIGGPDPRWAHLDWPAQQRAWEAEHRDGSGNGDGDRMGVAGDICEQEPETPSCPVKHTLMPELDF
  
Inhibitor
Name:
BDBM79411
Synonyms:
(E)-3-(1-benzofuran-2-yl)-1-(2-hydroxy-5-methoxyphenyl)prop-2-en-1-one | (E)-3-(1-benzofuran-2-yl)-1-(5-methoxy-2-oxidanyl-phenyl)prop-2-en-1-one | (E)-3-(2-benzofuranyl)-1-(2-hydroxy-5-methoxyphenyl)-2-propen-1-one | (E)-3-(benzofuran-2-yl)-1-(2-hydroxy-5-methoxy-phenyl)prop-2-en-1-one | 3-(1-benzofuran-2-yl)-1-(2-hydroxy-5-methoxyphenyl)-2-propen-1-one | MLS000575293 | SMR000196527 | cid_5734190
Type:
Small organic molecule
Emp. Form.:
C18H14O4
Mol. Mass.:
294.3014
SMILES:
COc1ccc(O)c(c1)C(=O)\C=C\c1cc2ccccc2o1
Structure:
Search PDB for entries with ligand similarity: