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Target
Perilipin-5
Ligand
BDBM79416
Substrate
n/a
Meas. Tech.
Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain
IC50
2798±n/a nM
Citation
 PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) (2K validation set) PubChem Bioassay (2011)[AID] 
Target
Name:
Perilipin-5
Synonyms:
LSDP5 | OXPAT | PAT-1 | PLIN5 | PLIN5_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50774.20
Organism:
Homo sapiens (Human)
Description:
gi_116292172
Residue:
463
Sequence:
MSEEEAAQIPRSSVWEQDQQNVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSACRLAENCVCGLTTRALDHAQPLLEHLQPQLATMNSLACRGLDKLEEKLPFLQQPSETVVTSAKDVVASSVTGVVDLARRGRRWSVELKRSVSHAVDVVLEKSEELVDHFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLGSLSARIRHLAYEHSVGKLRQSKHRAQDTLAQLQETLELIDHMQCGVTPTAPACPGKVHELWGEWGQRPPESRRRSQAELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVAEVRRSVDALQTAFADARCFRDVPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGPFAPILVERPEPLPDLADLVDEVIGGPDPRWAHLDWPAQQRAWEAEHRDGSGNGDGDRMGVAGDICEQEPETPSCPVKHTLMPELDF
  
Inhibitor
Name:
BDBM79416
Synonyms:
(5E)-5-(4,5-dimethoxy-2-nitro-benzylidene)-1-p-phenetyl-barbituric acid | (5E)-5-[(4,5-dimethoxy-2-nitro-phenyl)methylidene]-1-(4-ethoxyphenyl)-1,3-diazinane-2,4,6-trione | (5E)-5-[(4,5-dimethoxy-2-nitrophenyl)methylidene]-1-(4-ethoxyphenyl)-1,3-diazinane-2,4,6-trione | 5-(4,5-dimethoxy-2-nitrobenzylidene)-1-(4-ethoxyphenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione | MLS000683397 | SMR000267866 | cid_2261569
Type:
Small organic molecule
Emp. Form.:
C21H19N3O8
Mol. Mass.:
441.3909
SMILES:
CCOc1ccc(cc1)N1C(=O)NC(=O)C(=Cc2cc(OC)c(OC)cc2[N+]([O-])=O)C1=O |w:16.17|
Structure:
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