Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM67724
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
550±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM67724
Synonyms:
(3-methoxyphenyl)-[1-(m-tolyl)pyrazolo[3,4-d]pyrimidin-4-yl]amine | MLS000077456 | N-(3-methoxyphenyl)-1-(3-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinamine | N-(3-methoxyphenyl)-1-(3-methylphenyl)pyrazolo[3,4-d]pyrimidin-4-amine | SMR000035757 | cid_661236
Type:
Small organic molecule
Emp. Form.:
C19H17N5O
Mol. Mass.:
331.3712
SMILES:
COc1cccc(Nc2ncnc3n(ncc23)-c2cccc(C)c2)c1
Structure:
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