Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM66392
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
>10000±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM66392
Synonyms:
2,2-bis(4-methylphenyl)-N-(4-nitro-2-oxidanyl-phenyl)cyclopropane-1-carboxamide | MLS000579026 | N-(2-hydroxy-4-nitro-phenyl)-2,2-bis(p-tolyl)cyclopropanecarboxamide | N-(2-hydroxy-4-nitrophenyl)-2,2-bis(4-methylphenyl)-1-cyclopropanecarboxamide | N-(2-hydroxy-4-nitrophenyl)-2,2-bis(4-methylphenyl)cyclopropane-1-carboxamide | N-(2-hydroxy-4-nitrophenyl)-2,2-bis(4-methylphenyl)cyclopropanecarboxamide | SMR000186615 | cid_3375236
Type:
Small organic molecule
Emp. Form.:
C24H22N2O4
Mol. Mass.:
402.4425
SMILES:
Cc1ccc(cc1)C1(CC1C(=O)Nc1ccc(cc1O)[N+]([O-])=O)c1ccc(C)cc1
Structure:
Search PDB for entries with ligand similarity: