Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM68010
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
<160±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM68010
Synonyms:
(2Z,6E)-4-tert-butyl-2,6-bis(2-furanylmethylidene)-1-cyclohexanone | (2Z,6E)-4-tert-butyl-2,6-bis(2-furfurylidene)cyclohexanone | (2Z,6E)-4-tert-butyl-2,6-bis(2-furylmethylene)cyclohexanone | (2Z,6E)-4-tert-butyl-2,6-bis(furan-2-ylmethylidene)cyclohexan-1-one | MLS000580624 | SMR000204787 | cid_12004979
Type:
Small organic molecule
Emp. Form.:
C20H22O3
Mol. Mass.:
310.3869
SMILES:
CC(C)(C)C1C\C(=C\c2ccco2)C(=O)\C(C1)=C\c1ccco1
Structure:
Search PDB for entries with ligand similarity: