Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM65549
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
<160±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM65549
Synonyms:
3-[[4-[2-(3-chloroanilino)-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol | 3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]-2-pyridyl]amino]propan-1-ol | 3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol | 3-[[4-[2-[(3-chlorophenyl)amino]pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol | MLS000911536 | SMR000463552 | cid_644215
Type:
Small organic molecule
Emp. Form.:
C18H18ClN5O
Mol. Mass.:
355.821
SMILES:
OCCCNc1cc(ccn1)-c1ccnc(Nc2cccc(Cl)c2)n1
Structure:
Search PDB for entries with ligand similarity: