Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM68194
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
300±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM68194
Synonyms:
3-[4-[(2,5-difluorobenzyl)amino]-3-nitro-phenyl]-3-[[2-(1-naphthyl)acetyl]amino]propionamide | 3-[4-[(2,5-difluorophenyl)methylamino]-3-nitrophenyl]-3-[(2-naphthalen-1-ylacetyl)amino]propanamide | 3-[4-[(2,5-difluorophenyl)methylamino]-3-nitrophenyl]-3-[[2-(1-naphthalenyl)-1-oxoethyl]amino]propanamide | 3-[4-[[2,5-bis(fluoranyl)phenyl]methylamino]-3-nitro-phenyl]-3-(2-naphthalen-1-ylethanoylamino)propanamide | MLS000420567 | SMR000463427 | cid_16746181
Type:
Small organic molecule
Emp. Form.:
C28H24F2N4O4
Mol. Mass.:
518.5114
SMILES:
NC(=O)CC(NC(=O)Cc1cccc2ccccc12)c1ccc(NCc2cc(F)ccc2F)c(c1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: