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Target
Caspase-7
Ligand
BDBM79434
Substrate
n/a
Meas. Tech.
Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7
EC50
>85301±n/a nM
Citation
 PubChem, PC Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7 PubChem Bioassay (2011)[AID] 
Target
Name:
Caspase-7
Synonyms:
Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase
Type:
Enzyme
Mol. Mass.:
34273.91
Organism:
Homo sapiens (Human)
Description:
P55210
Residue:
303
Sequence:
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
  
Inhibitor
Name:
BDBM79434
Synonyms:
(2-oxidanylideneoxolan-3-yl) 2-(4-methoxyphenyl)quinoline-4-carboxylate | (2-oxooxolan-3-yl) 2-(4-methoxyphenyl)quinoline-4-carboxylate | 2-(4-methoxyphenyl)-4-quinolinecarboxylic acid (2-oxo-3-oxolanyl) ester | 2-(4-methoxyphenyl)cinchoninic acid (2-ketotetrahydrofuran-3-yl) ester | MLS000564384 | SMR000151943 | cid_3690908
Type:
Small organic molecule
Emp. Form.:
C21H17NO5
Mol. Mass.:
363.3634
SMILES:
COc1ccc(cc1)-c1cc(C(=O)OC2CCOC2=O)c2ccccc2n1
Structure:
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