Reaction Details Report a problem with these data
Target
Caspase-7
Ligand
BDBM79435
Substrate
n/a
Meas. Tech.
Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7
EC50
>85309±n/a nM
Citation
 PubChem, PC Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7 PubChem Bioassay (2011)[AID] 
Target
Name:
Caspase-7
Synonyms:
Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase
Type:
Enzyme
Mol. Mass.:
34273.91
Organism:
Homo sapiens (Human)
Description:
P55210
Residue:
303
Sequence:
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
  
Inhibitor
Name:
BDBM79435
Synonyms:
(E)-2-Cyano-3-(2,5-dimethoxy-phenylamino)-acrylic acid ethyl ester | (E)-2-cyano-3-(2,5-dimethoxyanilino)-2-propenoic acid ethyl ester | (E)-2-cyano-3-(2,5-dimethoxyanilino)acrylic acid ethyl ester | MLS000590927 | SMR000217816 | cid_1957350 | ethyl (E)-2-cyano-3-(2,5-dimethoxyanilino)prop-2-enoate | ethyl (E)-2-cyano-3-[(2,5-dimethoxyphenyl)amino]prop-2-enoate
Type:
Small organic molecule
Emp. Form.:
C14H16N2O4
Mol. Mass.:
276.2878
SMILES:
CCOC(=O)C(C=Nc1cc(OC)ccc1OC)C#N |w:7.7|
Structure:
Search PDB for entries with ligand similarity: