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Target
Caspase-7
Ligand
BDBM79438
Substrate
n/a
Meas. Tech.
Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7
EC50
>85284±n/a nM
Citation
 PubChem, PC Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7 PubChem Bioassay (2011)[AID] 
Target
Name:
Caspase-7
Synonyms:
Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase
Type:
Enzyme
Mol. Mass.:
34273.91
Organism:
Homo sapiens (Human)
Description:
P55210
Residue:
303
Sequence:
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
  
Inhibitor
Name:
BDBM79438
Synonyms:
2-[4-[(2,5-dimethoxybenzyl)carbamoyl]piperidino]-N-(3-methoxyphenyl)isonicotinamide | 2-[4-[(2,5-dimethoxyphenyl)methylcarbamoyl]piperidin-1-yl]-N-(3-methoxyphenyl)pyridine-4-carboxamide | 2-[4-[[(2,5-dimethoxyphenyl)methylamino]-oxomethyl]-1-piperidinyl]-N-(3-methoxyphenyl)-4-pyridinecarboxamide | MLS000924798 | SMR000623699 | cid_20867012
Type:
Small organic molecule
Emp. Form.:
C28H32N4O5
Mol. Mass.:
504.5775
SMILES:
COc1cccc(NC(=O)c2ccnc(c2)N2CCC(CC2)C(=O)NCc2cc(OC)ccc2OC)c1
Structure:
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