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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM66449
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based assay provider high throughput dose response assay for partial agonists of the peroxisome proliferator-activated receptor gamma (PPARg)
EC50
1800±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based assay provider high throughput dose response assay for partial agonists of the peroxisome proliferator-activated receptor gamma (PPARg) PubChem Bioassay (2011)[AID] 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2
Type:
Nuclear Receptor
Mol. Mass.:
57613.46
Organism:
Homo sapiens (Human)
Description:
P37231
Residue:
505
Sequence:
MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM66449
Synonyms:
2-[3-(4-fluorobenzoyl)-4-keto-6-methoxy-1-quinolyl]-N-(4-fluorophenyl)acetamide | 2-[3-(4-fluorobenzoyl)-6-methoxy-4-oxoquinolin-1-yl]-N-(4-fluorophenyl)acetamide | MLS000724725 | N-(4-fluorophenyl)-2-[3-(4-fluorophenyl)carbonyl-6-methoxy-4-oxidanylidene-quinolin-1-yl]ethanamide | N-(4-fluorophenyl)-2-[3-[(4-fluorophenyl)-oxomethyl]-6-methoxy-4-oxo-1-quinolinyl]acetamide | SMR000237569 | cid_2135407
Type:
Small organic molecule
Emp. Form.:
C25H18F2N2O4
Mol. Mass.:
448.4182
SMILES:
COc1ccc2n(CC(=O)Nc3ccc(F)cc3)cc(C(=O)c3ccc(F)cc3)c(=O)c2c1
Structure:
Search PDB for entries with ligand similarity: