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Target
Sphingosine 1-phosphate receptor 4
Ligand
BDBM79475
Substrate
n/a
Meas. Tech.
Late-stage fluorescence dose response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): purchased compounds EC50
EC50
>50000±n/a nM
Citation
 PubChem, PC Late-stage fluorescence dose response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): purchased compounds EC50 PubChem Bioassay (2011)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 4
Synonyms:
EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41647.39
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
384
Sequence:
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
  
Inhibitor
Name:
BDBM79475
Synonyms:
N-(3,5-dichlorophenyl)-2-(6-methyl-2-nitropyridin-3-yl)oxyacetamide | N-(3,5-dichlorophenyl)-2-[(6-methyl-2-nitro-3-pyridinyl)oxy]acetamide | N-(3,5-dichlorophenyl)-2-[(6-methyl-2-nitro-3-pyridyl)oxy]acetamide | N-[3,5-bis(chloranyl)phenyl]-2-(6-methyl-2-nitro-pyridin-3-yl)oxy-ethanamide | SR-02000000317 | SR-02000000317-1 | cid_3418421
Type:
Small organic molecule
Emp. Form.:
C14H11Cl2N3O4
Mol. Mass.:
356.161
SMILES:
Cc1ccc(OCC(=O)Nc2cc(Cl)cc(Cl)c2)c(n1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: