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Target
Sphingosine 1-phosphate receptor 4
Ligand
BDBM79478
Substrate
n/a
Meas. Tech.
Late-stage fluorescence dose response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): purchased compounds EC50
EC50
>50000±n/a nM
Citation
 PubChem, PC Late-stage fluorescence dose response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): purchased compounds EC50 PubChem Bioassay (2011)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 4
Synonyms:
EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41647.39
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
384
Sequence:
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
  
Inhibitor
Name:
BDBM79478
Synonyms:
3-(3,5-dichloropyridin-2-yl)oxy-6-methyl-2-nitropyridine | 3-[(3,5-dichloro-2-pyridinyl)oxy]-6-methyl-2-nitropyridine | 3-[(3,5-dichloro-2-pyridyl)oxy]-6-methyl-2-nitro-pyridine | 3-[3,5-bis(chloranyl)pyridin-2-yl]oxy-6-methyl-2-nitro-pyridine | SR-02000000319 | SR-02000000319-1 | cid_4808983
Type:
Small organic molecule
Emp. Form.:
C11H7Cl2N3O3
Mol. Mass.:
300.098
SMILES:
Cc1ccc(Oc2ncc(Cl)cc2Cl)c(n1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: