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Target
Sphingosine 1-phosphate receptor 4
Ligand
BDBM79479
Substrate
n/a
Meas. Tech.
Late-stage fluorescence dose response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): purchased compounds EC50
EC50
>50000±n/a nM
Citation
 PubChem, PC Late-stage fluorescence dose response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): purchased compounds EC50 PubChem Bioassay (2011)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 4
Synonyms:
EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41647.39
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
384
Sequence:
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
  
Inhibitor
Name:
BDBM79479
Synonyms:
2-chloranyl-7,8-dimethyl-3-[(6-methyl-2-nitro-pyridin-3-yl)oxymethyl]quinoline | 2-chloro-7,8-dimethyl-3-[(6-methyl-2-nitro-3-pyridinyl)oxymethyl]quinoline | 2-chloro-7,8-dimethyl-3-[(6-methyl-2-nitro-3-pyridyl)oxymethyl]quinoline | 2-chloro-7,8-dimethyl-3-[(6-methyl-2-nitropyridin-3-yl)oxymethyl]quinoline | SR-02000000320 | SR-02000000320-1 | cid_16337919
Type:
Small organic molecule
Emp. Form.:
C18H16ClN3O3
Mol. Mass.:
357.791
SMILES:
Cc1ccc(OCc2cc3ccc(C)c(C)c3nc2Cl)c(n1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: