Target
Mitochondrial import inner membrane translocase subunit TIM23
Ligand
BDBM78356
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent tim23-1 yeast counterscreen.
IC50
11600±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent tim23-1 yeast counterscreen. PubChem Bioassay (2011)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM23
Synonyms:
MAS6 | MIM23 | MPI3 | TIM23 | TIM23_YEAST | TPA: Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23245.32
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285814664
Residue:
222
Sequence:
MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNIISGPGGMHVDTARLHPLAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYGTGAVYLLGLGIGGFSGMMQGLQNIPPNSPGKLQLNTVLNHITKRGPFLGNNAGILALSYNIINSTIDALRGKHDTAGSIGAGALTGALFKSSKGLKPMGYSSAMVAAACAVWCSVKKRLLEK
  
Inhibitor
Name:
BDBM78356
Synonyms:
4-[4-({4-nitrophenyl}diazenyl)(methyl)anilino]butanoic acid | 4-[N-methyl-4-(4-nitrophenyl)azo-anilino]butyric acid | 4-[N-methyl-4-(4-nitrophenyl)azoanilino]butanoic acid | 4-[N-methyl-4-[(4-nitrophenyl)diazenyl]anilino]butanoic acid | 4-[methyl-[4-[(4-nitrophenyl)diazenyl]phenyl]amino]butanoic acid | MLS001178741 | SMR000475642 | cid_4162554
Type:
Small organic molecule
Emp. Form.:
C17H18N4O4
Mol. Mass.:
342.3492
SMILES:
CN(CCCC(O)=O)c1ccc(cc1)\N=N\c1ccc(cc1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: