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Target
Neurotensin receptor type 1
Ligand
BDBM79518
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
>40000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79518
Synonyms:
5-bromanyl-2-ethoxy-N-(2-morpholin-4-ylphenyl)benzenesulfonamide | 5-bromo-2-ethoxy-N-(2-morpholin-4-ylphenyl)benzenesulfonamide | 5-bromo-2-ethoxy-N-(2-morpholinophenyl)benzenesulfonamide | 5-bromo-2-ethoxy-N-[2-(4-morpholinyl)phenyl]benzenesulfonamide | MLS000058079 | SMR000067502 | cid_2089876
Type:
Small organic molecule
Emp. Form.:
C18H21BrN2O4S
Mol. Mass.:
441.339
SMILES:
CCOc1ccc(Br)cc1S(=O)(=O)Nc1ccccc1N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: