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Target
Neurotensin receptor type 1
Ligand
BDBM44933
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
26400±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM44933
Synonyms:
4-(4-Benzhydryl-piperazin-1-yl)-[1,2,4]triazolo[4,3-a]quinoxaline | 4-(4-benzhydrylpiperazin-1-yl)-[1,2,4]triazolo[4,3-a]quinoxaline | 4-(4-benzhydrylpiperazino)-[1,2,4]triazolo[4,3-a]quinoxaline | 4-[4-(diphenylmethyl)-1-piperazinyl]-[1,2,4]triazolo[4,3-a]quinoxaline | 4-[4-(diphenylmethyl)piperazin-1-yl]-[1,2,4]triazolo[4,3-a]quinoxaline | MLS000554309 | SMR000146626 | cid_1894824
Type:
Small organic molecule
Emp. Form.:
C26H24N6
Mol. Mass.:
420.509
SMILES:
C1CN(CCN1C(c1ccccc1)c1ccccc1)c1nc2ccccc2n2cnnc12
Structure:
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