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Target
Neurotensin receptor type 1
Ligand
BDBM79529
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
14200±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79529
Synonyms:
1-[3-[1-(2-aminoethylsulfanyl)-2-nitroethyl]indol-1-yl]ethanone;hydrochloride | 1-[3-[1-(2-aminoethylthio)-2-nitro-ethyl]indol-1-yl]ethanone;hydrochloride | 1-[3-[1-(2-aminoethylthio)-2-nitroethyl]-1-indolyl]ethanone;hydrochloride | 1-[3-[1-(2-azanylethylsulfanyl)-2-nitro-ethyl]indol-1-yl]ethanone;hydrochloride | 1-{3-[1-(2-Amino-ethylsulfanyl)-2-nitro-ethyl]-indol-1-yl}-ethanone | MLS000558218 | SMR000148934 | cid_2827475
Type:
Small organic molecule
Emp. Form.:
C14H17N3O3S
Mol. Mass.:
307.368
SMILES:
CC(=O)n1cc(C(C[N+]([O-])=O)SCCN)c2ccccc12
Structure:
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