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Target
Neurotensin receptor type 1
Ligand
BDBM79530
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
19600±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79530
Synonyms:
(1-benzyl-4-piperidyl)-(2-phenylquinazolin-4-yl)amine | 2-phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine | 2-phenyl-N-[1-(phenylmethyl)piperidin-4-yl]quinazolin-4-amine | MLS000567698 | N-(1-benzylpiperidin-4-yl)-2-phenylquinazolin-4-amine | SMR000154183 | cid_4837288
Type:
Small organic molecule
Emp. Form.:
C26H26N4
Mol. Mass.:
394.5114
SMILES:
C(N1CCC(CC1)Nc1nc(nc2ccccc12)-c1ccccc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: