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Target
Neurotensin receptor type 1
Ligand
BDBM52323
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
7150±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM52323
Synonyms:
2-[4-keto-3-[2-keto-2-(tetrahydrofurfurylamino)ethyl]-5-[(6-methoxy-2-naphthyl)methylene]thiazolidin-2-ylidene]acetic acid ethyl ester | 2-[5-[(6-methoxy-2-naphthalenyl)methylidene]-4-oxo-3-[2-oxo-2-(2-oxolanylmethylamino)ethyl]-2-thiazolidinylidene]acetic acid ethyl ester | MLS000567764 | SMR000154339 | cid_4875908 | ethyl 2-[5-[(6-methoxynaphthalen-2-yl)methylidene]-4-oxidanylidene-3-[2-oxidanylidene-2-(oxolan-2-ylmethylamino)ethyl]-1,3-thiazolidin-2-ylidene]ethanoate | ethyl 2-[5-[(6-methoxynaphthalen-2-yl)methylidene]-4-oxo-3-[2-oxo-2-(oxolan-2-ylmethylamino)ethyl]-1,3-thiazolidin-2-ylidene]acetate
Type:
Small organic molecule
Emp. Form.:
C26H28N2O6S
Mol. Mass.:
496.575
SMILES:
CCOC(=O)C=c1sc(=Cc2ccc3cc(OC)ccc3c2)c(=O)n1CC(=O)NCC1CCCO1
Structure:
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