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Target
Neurotensin receptor type 1
Ligand
BDBM79537
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
12300±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79537
Synonyms:
MLS000595044 | N'-(1H-indol-3-ylmethylene)-2,2-diphenylcyclopropanecarbohydrazide | N'-[(Z)-3-indolylidenemethyl]-2,2-diphenyl-1-cyclopropanecarbohydrazide | N'-[(Z)-indol-3-ylidenemethyl]-2,2-diphenyl-cyclopropane-1-carbohydrazide | N'-[(Z)-indol-3-ylidenemethyl]-2,2-diphenyl-cyclopropanecarbohydrazide | N'-[(Z)-indol-3-ylidenemethyl]-2,2-diphenylcyclopropane-1-carbohydrazide | SMR000184430 | cid_5717454
Type:
Small organic molecule
Emp. Form.:
C25H21N3O
Mol. Mass.:
379.4537
SMILES:
O=C(NN=Cc1c[nH]c2ccccc12)C1CC1(c1ccccc1)c1ccccc1 |w:3.2|
Structure:
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