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Target
Neurotensin receptor type 1
Ligand
BDBM54254
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
8480±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM54254
Synonyms:
(E)-2-(1H-benzimidazol-2-yl)-3-(3-chlorophenyl)-1-phenyl-2-propen-1-one | (E)-2-(1H-benzimidazol-2-yl)-3-(3-chlorophenyl)-1-phenyl-prop-2-en-1-one | (E)-2-(1H-benzimidazol-2-yl)-3-(3-chlorophenyl)-1-phenylprop-2-en-1-one | MLS000390145 | SMR000259409 | cid_6122140
Type:
Small organic molecule
Emp. Form.:
C22H15ClN2O
Mol. Mass.:
358.82
SMILES:
Clc1cccc(\C=C(\C(=O)c2ccccc2)c2nc3ccccc3[nH]2)c1
Structure:
Search PDB for entries with ligand similarity: