Reaction Details Report a problem with these data
Target
Neurotensin receptor type 1
Ligand
BDBM79547
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
>40000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79547
Synonyms:
6-methyl-N-[(3-nitrophenyl)methylideneamino]-2-(trichloromethyl)-4-quinazolinamine | 6-methyl-N-[(3-nitrophenyl)methylideneamino]-2-(trichloromethyl)quinazolin-4-amine | MLS000374981 | SMR000254335 | [6-methyl-2-(trichloromethyl)quinazolin-4-yl]-[(3-nitrobenzylidene)amino]amine | cid_4143704
Type:
Small organic molecule
Emp. Form.:
C17H12Cl3N5O2
Mol. Mass.:
424.668
SMILES:
Cc1ccc2nc(nc(N=NCc3cccc(c3)[N+]([O-])=O)c2c1)C(Cl)(Cl)Cl |w:9.8|
Structure:
Search PDB for entries with ligand similarity: