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Target
Neurotensin receptor type 1
Ligand
BDBM66056
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
>40000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM66056
Synonyms:
(E)-3-(4-chloranyl-3-nitro-phenyl)-1-pyridin-3-yl-prop-2-en-1-one | (E)-3-(4-chloro-3-nitro-phenyl)-1-(3-pyridyl)prop-2-en-1-one | (E)-3-(4-chloro-3-nitrophenyl)-1-(3-pyridinyl)-2-propen-1-one | (E)-3-(4-chloro-3-nitrophenyl)-1-pyridin-3-ylprop-2-en-1-one | MLS000390403 | SMR000255370 | cid_6213986
Type:
Small organic molecule
Emp. Form.:
C14H9ClN2O3
Mol. Mass.:
288.686
SMILES:
[O-][N+](=O)c1cc(\C=C\C(=O)c2cccnc2)ccc1Cl
Structure:
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