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Target
Neurotensin receptor type 1
Ligand
BDBM79578
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
39300±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79578
Synonyms:
(5E)-1-[2-(4-fluorophenyl)ethyl]-5-[(E)-3-phenylprop-2-enylidene]-1,3-diazinane-2,4,6-trione | (5E)-1-[2-(4-fluorophenyl)ethyl]-5-[(E)-3-phenylprop-2-enylidene]barbituric acid | 1-[2-(4-Fluoro-phenyl)-ethyl]-5-[(E)-3-phenyl-prop-2-en-(E)-ylidene]-pyrimidine-2,4,6-trione | MLS000768280 | SMR000431601 | cid_1325215
Type:
Small organic molecule
Emp. Form.:
C21H17FN2O3
Mol. Mass.:
364.3697
SMILES:
Fc1ccc(CCN2C(=O)NC(=O)\C(=C/C=C/c3ccccc3)C2=O)cc1
Structure:
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