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Target
Neurotensin receptor type 1
Ligand
BDBM79579
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
8510±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79579
Synonyms:
4-(2-{N'-[1-Furan-2-yl-meth-(Z)-ylidene]-hydrazino}-thiazol-4-yl)-N,N-dimethyl-benzenesulfonamide | 4-[2-[2-(2-furanylmethylidene)hydrazinyl]-4-thiazolyl]-N,N-dimethylbenzenesulfonamide | 4-[2-[2-(furan-2-ylmethylidene)hydrazinyl]-1,3-thiazol-4-yl]-N,N-dimethyl-benzenesulfonamide | 4-[2-[2-(furan-2-ylmethylidene)hydrazinyl]-1,3-thiazol-4-yl]-N,N-dimethylbenzenesulfonamide | 4-[2-[N'-(2-furfurylidene)hydrazino]thiazol-4-yl]-N,N-dimethyl-benzenesulfonamide | MLS000778017 | SMR000414411 | cid_5091636
Type:
Small organic molecule
Emp. Form.:
C16H16N4O3S2
Mol. Mass.:
376.453
SMILES:
CN(C)S(=O)(=O)c1ccc(cc1)-c1csc(N=NCc2ccco2)n1 |w:16.16|
Structure:
Search PDB for entries with ligand similarity: