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Target
Neurotensin receptor type 1
Ligand
BDBM79581
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
14700±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79581
Synonyms:
1-(4-chlorophenyl)-2-phenyl-3-(1-piperidinyl)-1-propanone;hydrochloride | 1-(4-chlorophenyl)-2-phenyl-3-piperidin-1-yl-propan-1-one;hydrochloride | 1-(4-chlorophenyl)-2-phenyl-3-piperidin-1-ylpropan-1-one;hydrochloride | 1-(4-chlorophenyl)-2-phenyl-3-piperidino-propan-1-one;hydrochloride | MLS001173584 | SMR000538769 | cid_24747433
Type:
Small organic molecule
Emp. Form.:
C20H22ClNO
Mol. Mass.:
327.848
SMILES:
Clc1ccc(cc1)C(=O)C(CN1CCCCC1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: