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Target
Neurotensin receptor type 1
Ligand
BDBM79584
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
19400±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79584
Synonyms:
4-[4-(4-hydroxyphenyl)-2-phenyl-1H-pyrimidin-6-ylidene]-1-cyclohexa-2,5-dienone | 4-[4-(4-hydroxyphenyl)-2-phenyl-1H-pyrimidin-6-ylidene]cyclohexa-2,5-dien-1-one | 4-[6-(4-hydroxyphenyl)-2-phenylpyrimidin-4-yl]phenol | MLS001197006 | SMR000555712 | cid_5342475
Type:
Small organic molecule
Emp. Form.:
C22H16N2O2
Mol. Mass.:
340.3746
SMILES:
Oc1ccc(cc1)-c1cc(nc(n1)-c1ccccc1)-c1ccc(O)cc1
Structure:
Search PDB for entries with ligand similarity: