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Target
Neurotensin receptor type 1
Ligand
BDBM79596
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
15400±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79596
Synonyms:
2-(3-butan-2-ylsulfanyl-4-methoxy-phenyl)-N-butyl-6-methyl-imidazo[1,2-a]pyridin-3-amine | 2-(3-butan-2-ylsulfanyl-4-methoxyphenyl)-N-butyl-6-methylimidazo[1,2-a]pyridin-3-amine | 2-[3-(butan-2-ylthio)-4-methoxyphenyl]-N-butyl-6-methyl-3-imidazo[1,2-a]pyridinamine | MLS001065983 | SMR000814645 | butyl-[2-[4-methoxy-3-(sec-butylthio)phenyl]-6-methyl-imidazo[1,2-a]pyridin-3-yl]amine | cid_42600970
Type:
Small organic molecule
Emp. Form.:
C23H31N3OS
Mol. Mass.:
397.577
SMILES:
CCCCNc1c(nc2ccc(C)cn12)-c1ccc(OC)c(SC(C)CC)c1
Structure:
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