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Target
Neurotensin receptor type 1
Ligand
BDBM79600
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
19900±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79600
Synonyms:
4-N-(4-chlorophenyl)-5-N-[(1R)-1-phenylethyl]-1H-imidazole-4,5-dicarboxamide | MLS002206661 | N-(4-chlorophenyl)-N'-[(1R)-1-phenylethyl]-1H-imidazole-4,5-dicarboxamide | N4-(4-chlorophenyl)-N5-[(1R)-1-phenylethyl]-1H-imidazole-4,5-dicarboxamide | SMR001306496 | cid_42628331
Type:
Small organic molecule
Emp. Form.:
C19H17ClN4O2
Mol. Mass.:
368.817
SMILES:
C[C@@H](NC(=O)c1nc[nH]c1C(=O)Nc1ccc(Cl)cc1)c1ccccc1
Structure:
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