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Targetintegrin alpha-L
LigandBDBM79603
Substrate/Competitorn/a
Meas. Tech.Dose Response of Developing T Cell Immune Modulators with powder sourced compounds
EC50 299±n/a nM
Citation PubChem, PC Dose Response of Developing T Cell Immune Modulators with powder sourced compounds PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
integrin alpha-L
Name:integrin alpha-L
Synonyms:CD11 antigen-like family member A | Leukocyte adhesion glycoprotein LFA-1 alpha chain | Leukocyte function-associated molecule 1 alpha chain | Lymphocyte antigen 15
Type:Enzyme Catalytic Domain
Mol. Mass.:128317.79
Organism:Mus musculus
Description:P24063
Residue:1163
Sequence:
MSFRIAGPRLLLLGLQLFAKAWSYNLDTRPTQSFLAQAGRHFGYQVLQIEDGVVVGAPGE
GDNTGGLYHCRTSSEFCQPVSLHGSNHTSKYLGMTLATDAAKGSLLACDPGLSRTCDQNT
YLSGLCYLFPQSLEGPMLQNRPAYQECMKGKVDLVFLFDGSQSLDRKDFEKILEFMKDVM
RKLSNTSYQFAAVQFSTDCRTEFTFLDYVKQNKNPDVLLGSVQPMFLLTNTFRAINYVVA
HVFKEESGARPDATKVLVIITDGEASDKGNISAAHDITRYIIGIGKHFVSVQKQKTLHIF
ASEPVEEFVKILDTFEKLKDLFTDLQRRIYAIEGTNRQDLTSFNMELSSSGISADLSKGH
AVVGAVGAKDWAGGFLDLREDLQGATFVGQEPLTSDVRGGYLGYTVAWMTSRSSRPLLAA
GAPRYQHVGQVLLFQAPEAGGRWNQTQKIEGTQIGSYFGGELCSVDLDQDGEAELLLIGA
PLFFGEQRGGRVFTYQRRQSLFEMVSELQGDPGYPLGRFGAAITALTDINGDRLTDVAVG
APLEEQGAVYIFNGKPGGLSPQPSQRIQGAQVFPGIRWFGRSIHGVKDLGGDRLADVVVG
AEGRVVVLSSRPVVDVVTELSFSPEEIPVHEVECSYSAREEQKHGVKLKACFRIKPLTPQ
FQGRLLANLSYTLQLDGHRMRSRGLFPDGSHELSGNTSITPDKSCLDFHFHFPICIQDLI
SPINVSLNFSLLEEEGTPRDQKGRAMQPILRPSIHTVTKEIPFEKNCGEDKKCEANLTLS
SPARSGPLRLMSSASLAVEWTLSNSGEDAYWVRLDLDFPRGLSFRKVEMLQPHSRMPVSC
EELTEGSSLLTKTLKCNVSSPIFKAGQEVSLQVMFNTLLNSSWEDFVELNGTVHCENENS
SLQEDNSAATHIPVLYPVNILTKEQENSTLYISFTPKGPKTQQVQHVYQVRIQPSAYDHN
MPTLEALVGVPWPHSEDPITYTWSVQTDPLVTCHSEDLKRPSSEAEQPCLPGVQFRCPIV
FRREILIQVTGTVELSKEIKASSTLSLCSSLSVSFNSSKHFHLYGSKASEAQVLVKVDLI
HEKEMLHVYVLSGIGGLVLLFLIFLALYKVGFFKRNLKEKMEADGGVPNGSPPEDTDPLA
VPGEETKDMGCLEPSGRVTRTKA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM79603
NameBDBM79603
Synonyms:(3-chloranyl-6-fluoranyl-1-benzothiophen-2-yl)-(3,5-dimethylpyrazol-1-yl)methanone | (3-chloro-6-fluoro-1-benzothiophen-2-yl)-(3,5-dimethyl-1-pyrazolyl)methanone | (3-chloro-6-fluoro-1-benzothiophen-2-yl)-(3,5-dimethylpyrazol-1-yl)methanone | (3-chloro-6-fluoro-benzothiophen-2-yl)-(3,5-dimethylpyrazol-1-yl)methanone | VU0284248-2 | cid_2948628
TypeSmall organic molecule
Emp. Form.C14H10ClFN2OS
Mol. Mass.308.758
SMILESCc1cc(C)n(n1)C(=O)c1sc2cc(F)ccc2c1Cl
Structure
n/a