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Target
Integrin alpha-L
Ligand
BDBM79603
Substrate
n/a
Meas. Tech.
Dose Response of Developing T Cell Immune Modulators with powder sourced compounds
EC50
299±n/a nM
Citation
 PubChem, PC Dose Response of Developing T Cell Immune Modulators with powder sourced compounds PubChem Bioassay (2011)[AID] 
Target
Name:
Integrin alpha-L
Synonyms:
CD11 antigen-like family member A | ITAL_MOUSE | Itgal | Leukocyte adhesion glycoprotein LFA-1 alpha chain | Leukocyte function-associated molecule 1 alpha chain | Lfa-1 | Ly-15 | Lymphocyte antigen 15
Type:
Enzyme Catalytic Domain
Mol. Mass.:
128317.79
Organism:
Mus musculus
Description:
P24063
Residue:
1163
Sequence:
MSFRIAGPRLLLLGLQLFAKAWSYNLDTRPTQSFLAQAGRHFGYQVLQIEDGVVVGAPGEGDNTGGLYHCRTSSEFCQPVSLHGSNHTSKYLGMTLATDAAKGSLLACDPGLSRTCDQNTYLSGLCYLFPQSLEGPMLQNRPAYQECMKGKVDLVFLFDGSQSLDRKDFEKILEFMKDVMRKLSNTSYQFAAVQFSTDCRTEFTFLDYVKQNKNPDVLLGSVQPMFLLTNTFRAINYVVAHVFKEESGARPDATKVLVIITDGEASDKGNISAAHDITRYIIGIGKHFVSVQKQKTLHIFASEPVEEFVKILDTFEKLKDLFTDLQRRIYAIEGTNRQDLTSFNMELSSSGISADLSKGHAVVGAVGAKDWAGGFLDLREDLQGATFVGQEPLTSDVRGGYLGYTVAWMTSRSSRPLLAAGAPRYQHVGQVLLFQAPEAGGRWNQTQKIEGTQIGSYFGGELCSVDLDQDGEAELLLIGAPLFFGEQRGGRVFTYQRRQSLFEMVSELQGDPGYPLGRFGAAITALTDINGDRLTDVAVGAPLEEQGAVYIFNGKPGGLSPQPSQRIQGAQVFPGIRWFGRSIHGVKDLGGDRLADVVVGAEGRVVVLSSRPVVDVVTELSFSPEEIPVHEVECSYSAREEQKHGVKLKACFRIKPLTPQFQGRLLANLSYTLQLDGHRMRSRGLFPDGSHELSGNTSITPDKSCLDFHFHFPICIQDLISPINVSLNFSLLEEEGTPRDQKGRAMQPILRPSIHTVTKEIPFEKNCGEDKKCEANLTLSSPARSGPLRLMSSASLAVEWTLSNSGEDAYWVRLDLDFPRGLSFRKVEMLQPHSRMPVSCEELTEGSSLLTKTLKCNVSSPIFKAGQEVSLQVMFNTLLNSSWEDFVELNGTVHCENENSSLQEDNSAATHIPVLYPVNILTKEQENSTLYISFTPKGPKTQQVQHVYQVRIQPSAYDHNMPTLEALVGVPWPHSEDPITYTWSVQTDPLVTCHSEDLKRPSSEAEQPCLPGVQFRCPIVFRREILIQVTGTVELSKEIKASSTLSLCSSLSVSFNSSKHFHLYGSKASEAQVLVKVDLIHEKEMLHVYVLSGIGGLVLLFLIFLALYKVGFFKRNLKEKMEADGGVPNGSPPEDTDPLAVPGEETKDMGCLEPSGRVTRTKA
  
Inhibitor
Name:
BDBM79603
Synonyms:
(3-chloranyl-6-fluoranyl-1-benzothiophen-2-yl)-(3,5-dimethylpyrazol-1-yl)methanone | (3-chloro-6-fluoro-1-benzothiophen-2-yl)-(3,5-dimethyl-1-pyrazolyl)methanone | (3-chloro-6-fluoro-1-benzothiophen-2-yl)-(3,5-dimethylpyrazol-1-yl)methanone | (3-chloro-6-fluoro-benzothiophen-2-yl)-(3,5-dimethylpyrazol-1-yl)methanone | VU0284248-2 | cid_2948628
Type:
Small organic molecule
Emp. Form.:
C14H10ClFN2OS
Mol. Mass.:
308.758
SMILES:
Cc1cc(C)n(n1)C(=O)c1sc2cc(F)ccc2c1Cl
Structure:
Search PDB for entries with ligand similarity: