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Targetintegrin alpha-L
LigandBDBM79604
Substrate/Competitorn/a
Meas. Tech.Dose Response of Developing T Cell Immune Modulators with powder sourced compounds
EC50 17061±n/a nM
Citation PubChem, PC Dose Response of Developing T Cell Immune Modulators with powder sourced compounds PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
integrin alpha-L
Name:integrin alpha-L
Synonyms:CD11 antigen-like family member A | Leukocyte adhesion glycoprotein LFA-1 alpha chain | Leukocyte function-associated molecule 1 alpha chain | Lymphocyte antigen 15
Type:Enzyme Catalytic Domain
Mol. Mass.:128317.79
Organism:Mus musculus
Description:P24063
Residue:1163
Sequence:
MSFRIAGPRLLLLGLQLFAKAWSYNLDTRPTQSFLAQAGRHFGYQVLQIEDGVVVGAPGE
GDNTGGLYHCRTSSEFCQPVSLHGSNHTSKYLGMTLATDAAKGSLLACDPGLSRTCDQNT
YLSGLCYLFPQSLEGPMLQNRPAYQECMKGKVDLVFLFDGSQSLDRKDFEKILEFMKDVM
RKLSNTSYQFAAVQFSTDCRTEFTFLDYVKQNKNPDVLLGSVQPMFLLTNTFRAINYVVA
HVFKEESGARPDATKVLVIITDGEASDKGNISAAHDITRYIIGIGKHFVSVQKQKTLHIF
ASEPVEEFVKILDTFEKLKDLFTDLQRRIYAIEGTNRQDLTSFNMELSSSGISADLSKGH
AVVGAVGAKDWAGGFLDLREDLQGATFVGQEPLTSDVRGGYLGYTVAWMTSRSSRPLLAA
GAPRYQHVGQVLLFQAPEAGGRWNQTQKIEGTQIGSYFGGELCSVDLDQDGEAELLLIGA
PLFFGEQRGGRVFTYQRRQSLFEMVSELQGDPGYPLGRFGAAITALTDINGDRLTDVAVG
APLEEQGAVYIFNGKPGGLSPQPSQRIQGAQVFPGIRWFGRSIHGVKDLGGDRLADVVVG
AEGRVVVLSSRPVVDVVTELSFSPEEIPVHEVECSYSAREEQKHGVKLKACFRIKPLTPQ
FQGRLLANLSYTLQLDGHRMRSRGLFPDGSHELSGNTSITPDKSCLDFHFHFPICIQDLI
SPINVSLNFSLLEEEGTPRDQKGRAMQPILRPSIHTVTKEIPFEKNCGEDKKCEANLTLS
SPARSGPLRLMSSASLAVEWTLSNSGEDAYWVRLDLDFPRGLSFRKVEMLQPHSRMPVSC
EELTEGSSLLTKTLKCNVSSPIFKAGQEVSLQVMFNTLLNSSWEDFVELNGTVHCENENS
SLQEDNSAATHIPVLYPVNILTKEQENSTLYISFTPKGPKTQQVQHVYQVRIQPSAYDHN
MPTLEALVGVPWPHSEDPITYTWSVQTDPLVTCHSEDLKRPSSEAEQPCLPGVQFRCPIV
FRREILIQVTGTVELSKEIKASSTLSLCSSLSVSFNSSKHFHLYGSKASEAQVLVKVDLI
HEKEMLHVYVLSGIGGLVLLFLIFLALYKVGFFKRNLKEKMEADGGVPNGSPPEDTDPLA
VPGEETKDMGCLEPSGRVTRTKA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM79604
NameBDBM79604
Synonyms:2-[3-(2-bromanyl-6-chloranyl-4-methyl-phenoxy)propylsulfanyl]-6-methyl-1H-pyrimidin-4-one | 2-[3-(2-bromo-6-chloro-4-methyl-phenoxy)propylthio]-6-methyl-1H-pyrimidin-4-one | 2-[3-(2-bromo-6-chloro-4-methylphenoxy)propylsulfanyl]-6-methyl-1H-pyrimidin-4-one | 2-[3-(2-bromo-6-chloro-4-methylphenoxy)propylthio]-6-methyl-1H-pyrimidin-4-one | VU0170460-3 | cid_2216015
TypeSmall organic molecule
Emp. Form.C15H16BrClN2O2S
Mol. Mass.403.722
SMILESCc1cc(Cl)c(OCCCSc2nc(C)cc(=O)[nH]2)c(Br)c1
Structure
n/a