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Targetintegrin alpha-L
LigandBDBM79607
Substrate/Competitorn/a
Meas. Tech.Dose Response of Developing T Cell Immune Modulators with powder sourced compounds
EC50 19275±n/a nM
Citation PubChem, PC Dose Response of Developing T Cell Immune Modulators with powder sourced compounds PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
integrin alpha-L
Name:integrin alpha-L
Synonyms:CD11 antigen-like family member A | Leukocyte adhesion glycoprotein LFA-1 alpha chain | Leukocyte function-associated molecule 1 alpha chain | Lymphocyte antigen 15
Type:Enzyme Catalytic Domain
Mol. Mass.:128317.79
Organism:Mus musculus
Description:P24063
Residue:1163
Sequence:
MSFRIAGPRLLLLGLQLFAKAWSYNLDTRPTQSFLAQAGRHFGYQVLQIEDGVVVGAPGE
GDNTGGLYHCRTSSEFCQPVSLHGSNHTSKYLGMTLATDAAKGSLLACDPGLSRTCDQNT
YLSGLCYLFPQSLEGPMLQNRPAYQECMKGKVDLVFLFDGSQSLDRKDFEKILEFMKDVM
RKLSNTSYQFAAVQFSTDCRTEFTFLDYVKQNKNPDVLLGSVQPMFLLTNTFRAINYVVA
HVFKEESGARPDATKVLVIITDGEASDKGNISAAHDITRYIIGIGKHFVSVQKQKTLHIF
ASEPVEEFVKILDTFEKLKDLFTDLQRRIYAIEGTNRQDLTSFNMELSSSGISADLSKGH
AVVGAVGAKDWAGGFLDLREDLQGATFVGQEPLTSDVRGGYLGYTVAWMTSRSSRPLLAA
GAPRYQHVGQVLLFQAPEAGGRWNQTQKIEGTQIGSYFGGELCSVDLDQDGEAELLLIGA
PLFFGEQRGGRVFTYQRRQSLFEMVSELQGDPGYPLGRFGAAITALTDINGDRLTDVAVG
APLEEQGAVYIFNGKPGGLSPQPSQRIQGAQVFPGIRWFGRSIHGVKDLGGDRLADVVVG
AEGRVVVLSSRPVVDVVTELSFSPEEIPVHEVECSYSAREEQKHGVKLKACFRIKPLTPQ
FQGRLLANLSYTLQLDGHRMRSRGLFPDGSHELSGNTSITPDKSCLDFHFHFPICIQDLI
SPINVSLNFSLLEEEGTPRDQKGRAMQPILRPSIHTVTKEIPFEKNCGEDKKCEANLTLS
SPARSGPLRLMSSASLAVEWTLSNSGEDAYWVRLDLDFPRGLSFRKVEMLQPHSRMPVSC
EELTEGSSLLTKTLKCNVSSPIFKAGQEVSLQVMFNTLLNSSWEDFVELNGTVHCENENS
SLQEDNSAATHIPVLYPVNILTKEQENSTLYISFTPKGPKTQQVQHVYQVRIQPSAYDHN
MPTLEALVGVPWPHSEDPITYTWSVQTDPLVTCHSEDLKRPSSEAEQPCLPGVQFRCPIV
FRREILIQVTGTVELSKEIKASSTLSLCSSLSVSFNSSKHFHLYGSKASEAQVLVKVDLI
HEKEMLHVYVLSGIGGLVLLFLIFLALYKVGFFKRNLKEKMEADGGVPNGSPPEDTDPLA
VPGEETKDMGCLEPSGRVTRTKA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM79607
NameBDBM79607
Synonyms:1-[3-[(3,4-difluoroanilino)-oxomethyl]-4-fluorophenyl]sulfonyl-3-piperidinecarboxylic acid ethyl ester | 1-[3-[(3,4-difluorophenyl)carbamoyl]-4-fluoro-phenyl]sulfonylnipecotic acid ethyl ester | VU0424123-1 | cid_9551043 | ethyl 1-[3-[(3,4-difluorophenyl)carbamoyl]-4-fluorophenyl]sulfonylpiperidine-3-carboxylate | ethyl 1-[3-[[3,4-bis(fluoranyl)phenyl]carbamoyl]-4-fluoranyl-phenyl]sulfonylpiperidine-3-carboxylate
TypeSmall organic molecule
Emp. Form.C21H21F3N2O5S
Mol. Mass.470.462
SMILESCCOC(=O)C1CCCN(C1)S(=O)(=O)c1ccc(F)c(c1)C(=O)Nc1ccc(F)c(F)c1
Structure
n/a