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Targetintegrin alpha-L
LigandBDBM79615
Substrate/Competitorn/a
Meas. Tech.Dose Response of Developing T Cell Immune Modulators with powder sourced compounds
EC50 29107±n/a nM
Citation PubChem, PC Dose Response of Developing T Cell Immune Modulators with powder sourced compounds PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
integrin alpha-L
Name:integrin alpha-L
Synonyms:CD11 antigen-like family member A | Leukocyte adhesion glycoprotein LFA-1 alpha chain | Leukocyte function-associated molecule 1 alpha chain | Lymphocyte antigen 15
Type:Enzyme Catalytic Domain
Mol. Mass.:128317.79
Organism:Mus musculus
Description:P24063
Residue:1163
Sequence:
MSFRIAGPRLLLLGLQLFAKAWSYNLDTRPTQSFLAQAGRHFGYQVLQIEDGVVVGAPGE
GDNTGGLYHCRTSSEFCQPVSLHGSNHTSKYLGMTLATDAAKGSLLACDPGLSRTCDQNT
YLSGLCYLFPQSLEGPMLQNRPAYQECMKGKVDLVFLFDGSQSLDRKDFEKILEFMKDVM
RKLSNTSYQFAAVQFSTDCRTEFTFLDYVKQNKNPDVLLGSVQPMFLLTNTFRAINYVVA
HVFKEESGARPDATKVLVIITDGEASDKGNISAAHDITRYIIGIGKHFVSVQKQKTLHIF
ASEPVEEFVKILDTFEKLKDLFTDLQRRIYAIEGTNRQDLTSFNMELSSSGISADLSKGH
AVVGAVGAKDWAGGFLDLREDLQGATFVGQEPLTSDVRGGYLGYTVAWMTSRSSRPLLAA
GAPRYQHVGQVLLFQAPEAGGRWNQTQKIEGTQIGSYFGGELCSVDLDQDGEAELLLIGA
PLFFGEQRGGRVFTYQRRQSLFEMVSELQGDPGYPLGRFGAAITALTDINGDRLTDVAVG
APLEEQGAVYIFNGKPGGLSPQPSQRIQGAQVFPGIRWFGRSIHGVKDLGGDRLADVVVG
AEGRVVVLSSRPVVDVVTELSFSPEEIPVHEVECSYSAREEQKHGVKLKACFRIKPLTPQ
FQGRLLANLSYTLQLDGHRMRSRGLFPDGSHELSGNTSITPDKSCLDFHFHFPICIQDLI
SPINVSLNFSLLEEEGTPRDQKGRAMQPILRPSIHTVTKEIPFEKNCGEDKKCEANLTLS
SPARSGPLRLMSSASLAVEWTLSNSGEDAYWVRLDLDFPRGLSFRKVEMLQPHSRMPVSC
EELTEGSSLLTKTLKCNVSSPIFKAGQEVSLQVMFNTLLNSSWEDFVELNGTVHCENENS
SLQEDNSAATHIPVLYPVNILTKEQENSTLYISFTPKGPKTQQVQHVYQVRIQPSAYDHN
MPTLEALVGVPWPHSEDPITYTWSVQTDPLVTCHSEDLKRPSSEAEQPCLPGVQFRCPIV
FRREILIQVTGTVELSKEIKASSTLSLCSSLSVSFNSSKHFHLYGSKASEAQVLVKVDLI
HEKEMLHVYVLSGIGGLVLLFLIFLALYKVGFFKRNLKEKMEADGGVPNGSPPEDTDPLA
VPGEETKDMGCLEPSGRVTRTKA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM79615
NameBDBM79615
Synonyms:1-(2-methylbenzoyl)-N-(4-methyl-3-piperidin-1-ylsulfonylphenyl)piperidine-4-carboxamide | 1-(2-methylphenyl)carbonyl-N-(4-methyl-3-piperidin-1-ylsulfonyl-phenyl)piperidine-4-carboxamide | 1-[(2-methylphenyl)-oxomethyl]-N-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-4-piperidinecarboxamide | N-(4-methyl-3-piperidinosulfonyl-phenyl)-1-o-toluoyl-isonipecotamide | VU0424160-1 | cid_16277168
TypeSmall organic molecule
Emp. Form.C26H33N3O4S
Mol. Mass.483.623
SMILESCc1ccccc1C(=O)N1CCC(CC1)C(=O)Nc1ccc(C)c(c1)S(=O)(=O)N1CCCCC1
Structure
n/a