Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM46565
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen.
IC50
>100000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. PubChem Bioassay (2011)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM46565
Synonyms:
2-Chloro-1-(5-methyl-1H-indol-3-yl)-ethanone | 2-chloranyl-1-(5-methyl-1H-indol-3-yl)ethanone | 2-chloro-1-(5-methyl-1H-indol-3-yl)ethanone | MLS000559718 | SMR000178706 | cid_3159585
Type:
Small organic molecule
Emp. Form.:
C11H10ClNO
Mol. Mass.:
207.656
SMILES:
Cc1ccc2[nH]cc(C(=O)CCl)c2c1
Structure:
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