Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM71500
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen.
IC50
>100000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. PubChem Bioassay (2011)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM71500
Synonyms:
MLS001223930 | N-[(6-chloranyl-4-oxidanylidene-chromen-3-yl)methylideneamino]-4-methoxy-benzamide | N-[(6-chloro-4-keto-chromen-3-yl)methyleneamino]-4-methoxy-benzamide | N-[(6-chloro-4-oxo-1-benzopyran-3-yl)methylideneamino]-4-methoxybenzamide | N-[(6-chloro-4-oxochromen-3-yl)methylideneamino]-4-methoxybenzamide | SMR000678712 | cid_24819712
Type:
Small organic molecule
Emp. Form.:
C18H13ClN2O4
Mol. Mass.:
356.76
SMILES:
COc1ccc(cc1)C(=O)NN=Cc1coc2ccc(Cl)cc2c1=O
Structure:
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