Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM77926
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen.
IC50
>100000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. PubChem Bioassay (2011)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM77926
Synonyms:
MLS001142155 | N-(6-amino-1-butyl-2,4-diketo-pyrimidin-5-yl)-N-isoamyl-piperonylamide | N-(6-amino-1-butyl-2,4-dioxo-5-pyrimidinyl)-N-(3-methylbutyl)-1,3-benzodioxole-5-carboxamide | N-(6-amino-1-butyl-2,4-dioxopyrimidin-5-yl)-N-(3-methylbutyl)-1,3-benzodioxole-5-carboxamide | N-[6-azanyl-1-butyl-2,4-bis(oxidanylidene)pyrimidin-5-yl]-N-(3-methylbutyl)-1,3-benzodioxole-5-carboxamide | SMR000712508 | cid_24980190
Type:
Small organic molecule
Emp. Form.:
C21H28N4O5
Mol. Mass.:
416.4708
SMILES:
CCCCn1c(N)c(N(CCC(C)C)C(=O)c2ccc3OCOc3c2)c(=O)[nH]c1=O
Structure:
Search PDB for entries with ligand similarity: