Reaction Details Report a problem with these data
Target
Bcl-2-related protein A1
Ligand
BDBM58367
Substrate
n/a
Meas. Tech.
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
IC50
8260±147 nM
Citation
 PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM58367
Synonyms:
MLS001165405 | SMR000540005 | [(3Z)-3-(2-chloranylthioxanthen-9-ylidene)propyl]-dimethyl-undecyl-azanium;bromide | [(3Z)-3-(2-chloro-9-thioxanthenylidene)propyl]-dimethyl-undecylammonium;bromide | [(3Z)-3-(2-chlorothioxanthen-9-ylidene)propyl]-dimethyl-undecyl-ammonium;bromide | [(3Z)-3-(2-chlorothioxanthen-9-ylidene)propyl]-dimethyl-undecylazanium;bromide | cid_24747725
Type:
Small organic molecule
Emp. Form.:
C29H41ClNS
Mol. Mass.:
471.16
SMILES:
CCCCCCCCCCC[N+](C)(C)CC\C=C1\c2ccccc2Sc2ccc(Cl)cc12
Structure:
Search PDB for entries with ligand similarity: